Historical CMC projects that Eviva Pharma have worked on include experience of numerous dosage forms, from pre-clinical to late phase products, and as such offer consultancy that is broad based.
Further details of these historical CMC projects can be found below.
PRE-CLINICAL | ||
Type of Compound | Dose Form | Activity |
Synthetic compound | Oral | Analytical |
Kinase inhibitor | IV | Analytical |
Kallikrein inhibitor | Oral | Analytical |
PHASE I | ||
Type of Compound | Dose Form | Activity |
Monoclonal antibody | IV, Aqueous | Analytical |
Tetra peptide | Injection, Aqueous | Analytical |
Monoclonal antibody | IV, Aqueous | Analytical |
Monoclonal antibody | IV, Aqueous | Analytical |
Hsp inhibitor | IV, Lyophilised | Formulation development/Analytical |
Peptide | SC, Aqueous | Formulation development |
Monoclonal antibody | IV, Aqueous | Analytical |
Killed bacterial vaccine | Oral, Suspension | Formulation development/Analytical |
T-cell inhibitor | Oral | Analytical |
Thrombin inhibitor | IV | Formulation development |
PHASE II | ||
Type of Compound | Dose Form | Activity |
Monoclonal antibody | IV, Aqueous | Analytical |
Killed bacterial vaccine | Oral, Suspension | Formulation development/Analytical |
Conjugated angiotensin peptide | Injection, Aqueous | Analytical |
Synthetic compound derived from plants | IA, Surfactant solution | Formulation development |
Synthetic | IV, Aqueous | Formulation development |
Synthetic MDR | Oral, soft gel capsule | Formulation development |
Synthetic MDR | IV, Co-solvent | Formulation development |
PHASE III/IV | ||
Type of Compound | Dose Form | Activity |
Active metabolite of morphine | IV, Aqueous | Analytical |
Cocaine conjugate | Injection, Aqueous | Analytical |
PAF antagonist | IV, Aqueous | Formulation development |
Synthetic | Oral, Tablet | Expert report |
Synthetic phosphodiesterase inhibitor | IV, Co-solvent | Formulation development |
Semi synthetic glycopeptide | IV, Lyophilised | Formulation development |
Synthetic | Oral, Tablet | Expert report |
MARKETED | ||
Type of Compound | Dose Form | Activity |
Anti-venom | IV, Lyophilised | Analytical |